Evidence Based Medicine
What is Evidence Based Medicine
The most commonly used definition for EBM is that "Evidence-based medicine is the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of individual patients. The practice of evidence-based medicine means integrating individual clinical expertise with the best available external clinical evidence from systematic research." provided by David Sackett et al in the 1996 article, " Evidence-Based Medicine: What it is and what it isn't" for BMJ. Full text here
Levels of Evidence
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Understanding 'Levels of Evidence'
Developed by the Physiotherapy Association of British Columbia this tutorial explains the levels of evidence, based on research study design, so that you can find the best evidence for your practice using a database
Five 'A's of the Decision Making Cycle
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The Center for Evidence Based Managment (CEBMa) recommends that researchers consider the following questions in regard to published research and evidence. The process of evaluating evidence is known as critical appraisal.
1. Is the evidence from a known, reputable source?
2. Has the evidence been evaluated in any way? If so, how and by whom?
3. How up-to-date is the evidence?
CEBMa offers tools to help appraise research studies in the form of Critical Appraisal Checklists; you can set up a free account to access these resources.
Center of Evidence Based Medicine: Study Designs
According to the Center of Evidence Based Medicine, study designs include:
A defined population (P) from which groups of subjects are studied
Outcomes (O) that are measured
Experimental and analytic observational studies also include:
Interventions (I) or exposures (E) that are applied to different groups of subjects
Click here to go to a description of each research study type, including strengths and weaknesses
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What is PICO?
PICO is a mnemonic used to aide the clinician or researcher in identifying the important parts of a well-defined clinical question. This question then provides the basis for a search of medical literature on the question topic.
Elements of a Clinical Question
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Types of Possible Questions in Relation to PICO
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PICO Search
From The American Journal of Nursing
Evidence-Based Practice Part 1 : Developing and Searching the Clinical Question
Evidence-Based Practice, Part 2 : Critical Appraisal of the Evidence
Evidence-Based Practice Part 3 : Implementation
Evidence-Based Practice Part 4 : Disseminating the Evidence and Sustaining the Change
- EBP 2.0: From Strategy to Implementation
- EBP 2.0: Promoting Nurse Retention through Career Development Planning
- EBP 2.0: Data-Driven Precision Implementation Approach
- EBP 2.0: Implementing and Sustaining Change: The STAND Skin Bundle
- EBP 2.0: Implementing and Sustaining Change: The Malnutrition Readmission Prevention Protocol
- EBP 2.0: Implementing and Sustaining Change: The Evidence-Based Practice and Research Fellowship Program
- EBP 2.0: Implementing and Sustaining Change: Implementing Improved Central Line Flushing Practices
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AMSTAR 2AMSTAR stands for A MeaSurement Tool to Assess systematic Reviews. This instrument was developed by the Bruyere Research Institute to assess the methodological quality of systematic reviews.
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CASP (Critical Appraisal Skills Programme)"This set of eight critical appraisal tools are designed to be used when reading research, these include tools for Systematic Reviews, Randomised Controlled Trials, Cohort Studies, Case Control Studies, Economic Evaluations, Diagnostic Studies, Qualitative studies and Clinical Prediction Rule."
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CEBM. Critical Appraisal Tools.Contains useful tools and downloads for the critical appraisal of different types of medical evidence.
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Cochrane Risk-of-Bias tool for Randomized TrialsRoB2 - RoB 2: A revised Cochrane risk-of-bias tool for randomized trials. It is the recommended tool to assess the risk of bias in randomized trials included in Cochrane Reviews. RoB 2 is structured into a fixed set of domains of bias, focusing on different aspects of trial design, conduct, and reporting.
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Dartmouth Biomedical Libraries. Evidence-Based Medicine Worksheets.critical appraisal worksheets for therapy, diagnostic, prognosis, etiology, & qualitative studies, and practice guidelines & systematic reviews
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Duke University Medical Center Library. Evidence-Based Practice: AppraiseCritical appraisal worksheets for therapy, diagnosis, prognosis, qualitative studies, and more.
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Joanna Briggs Institute (JBI). Critical Appraisal Tools"JBI’s critical appraisal tools assist in assessing the trustworthiness, relevance and results of published papers." Includes checklists for 13 types of articles.
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Temple University Library. Critical Appraisal Checklists by Specific Study Design TypeLibrary guide with lists of critical appraisal checklists and tools.